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Dr Earl Prinsloo

Biography
  • Head of Department & Senior Lecturer in Biotechnology - Biotechnology Innovation Centre (July 2015- Current)
  • Senior Lecturer in Biotechnology- Biotechnology Innovation Centre, Rhodes University
  • Rhodes/Krege Foundation Lecturer in Biotechnology 2012-2014 - Department of Biochemistry, Microbiology and Biotechnology/Biotechnology Innovation Centre, Rhodes University.
  • Junior Lecturer in Biotechnology 2011 - Department of Biochemistry, Microbiology and Biotechnology, Rhodes University.
  • Claude Leon Foundation Postdoctoral Fellow 2008-2010 - Biomedical Biotechnology Research Unit, Rhodes University.
  • NRF Innovation Fund Postdoctoral Fellow 2007 - Chaperone Research Group, Rhodes University.
  • Ph.D (Microbiology) 2006 - Department of Biochemistry and Microbiology, Nelson Mandela Metropolitan University.
Research Focus

My research focuses on the role of mitochondria in stem cell biology and application of this knowledge to tissue engineering using additive manufacturing (Bioprinting) systems. Stem cells hold great promise for the future of regenerative medicine and drug discovery. Understanding the regulatory balance that maintains stem cell self-renewal and differentiation will allow for the biotechnological exploitation of this biomedical resource in tissue engineering.

Current research projects include:
  • Novel factors regulating adipogenesis
  • Directed differentiation of mesenchymal stem cells and neural stem cells
  • Protein-protein and protein-small molecule interactions regulating novel signalling protein localisation
  • Development of novel scaffolds for 3D tissue culture for stem cell maintenance and differentiation
  • Development of novel low cost bioprinting units for 3D tissue engineering
  • Design and development of low cost automated microscopy units.
Students

2017

  • Rose Kadye Ph.D (Biotechnology)
  • Pascalene Houseman M.Sc (Biotechnology) - submitted/pending
  • Sinethemba Mtwebana M.Sc (Biotechnology) - submitted/pending
  • Jethro Hundling M.Sc (Biotechnology)
  • Lucas Lotter M.Sc (Biotechnology)
  • Craige Bell B.Sc (Hons) (Biotechnology)
  • Warren Botha B.Sc (Hons) (Biotechnology)
  • Sidne Fanucci B.Sc (Hons) (Biotechnology)
  • Mihlali Stoffels B.Sc (Hons) (Biotechnology)

2016

  • John Honiball M.Sc (Biotechnology) with Distinction
  • Lebohang Makhene M.Sc (Biotechnology)
  • Samantha Whitehorn B.Sc Hons (Biotechnology) with Disctinction
  • Alan Tout B.Sc Hons (Biotechnology) with Distinction
  • Avuyonke Balfour B.Sc Hons (Biotechnology)
  • Justin Moorcroft B.Sc Hons (Joint Biotechnology & Physics and Electronics)

 2015

  • Julia Joos-Vandewalle M.Sc with Distinction (Biotechnology)

2014

  • John Honiball B.Sc Hons with Distinction (Biotechnology)
  • Pascalene Houseman B.Sc Hons (Biotechnology)
  • Lebohang Makhene B.Sc Hons (Biotechnology)
  • Sinethemba Mtwebana B.Sc Hons (Biotechnology)

2013

  • Rose Kadye M.Sc with Distinction (Biotechnology)
  • Adam H. Kramer M.Sc (Biotechnology)
  • Cathrine Moffit B.Sc Honours (Biotechnology)
  • Nontuthuzelo Ngxakaza B.Sc Honours (Biotechnology)
  • Tatenda Mutimutema B.Sc Honours (Biotechnology)

2012

  • Michelle Parsons B.Sc Honours (Biotechnology)
  • Zikhona Njengele B.Sc Honours (Biotechnology)
Latest Group Publications
  • Kramer, A. H., Kadye, R., Houseman, P. S., & Prinsloo, E. (2015). Mitochondrial STAT3 and reactive oxygen species: A fulcrum of adipogenesis?. JAK-STAT4(2), 1-10. http://dx.doi.org/10.1080/21623996.2015.1084084
  • Kramer, A. H., Edkins, A. L., Hoppe, H. C. and Prinsloo, E. (2015), Dynamic Mitochondrial Localisation of STAT3 in the Cellular Adipogenesis Model 3T3-L1. J. Cell. Biochem., 116: 1232–1240. doi:10.1002/jcb.25076
  • Kramer, A. H., Joos-Vandewalle, J., Edkins, A. L., Frost, C. L., & Prinsloo, E. (2014). Real-time monitoring of 3T3-L1 preadipocyte differentiation using a commercially available electric cell-substrate impedance sensor system.Biochemical and biophysical research communicationshttp://dx.doi.org/10.1016/j.bbrc.2013.12.123

Google Scholar list of publications

Funding
  • Research Commitee, Rhodes University
  • National Research Foundation Thuthuka Programme
Contact and Equipment Booking

Biotechnology Innovation Centre, PO Box 94, Rhodes  University, Grahamstown, 6140

 +27466038082 (office)

 +27466037576 (fax)

 e.prinsloo@ru.ac.za

For booking and use of the BioRad ProteOn XPR36 Interaction Array System, Roche xCELLigence Real Time Cell Analyser SP or the Zeiss AxioVert.A1 FL-LED Inverted Microscope please see links below

Last Modified :Wed, 17 May 2017 10:17:27 SAST