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Dr Philani N. Mashazi

Headshot Dr Mashazi



Dr Mashazi, spent 7 years at the Council for Minerals Technology (Mintek) as a research scientist from February 2007 to September 2013. During his tenure at Mintek, Dr Mashazi studied his doctoral degree part-time and graduated with the Doctor of Philosophy (PhD) degree at Rhodes University in April 2012. He rejoins Rhodes University Chemistry Department as a Senior Lecturer of Inorganic Chemistry since October 2013. He is currently involved in many departmental activities whilst pursuing his research interests. He further provides support to the National Facility funded by the Department of Science and Technology, the Nanotechnology Innovation Centre (DST NIC). He manages two state-of-the-art equipments, that is the X-ray photoelectron spectroscopy (XPS) and the soon-to-be-commissioned TOF-SIMS (Time-of-flight Secondary Ion Mass Spectrometry). Both these techniques are a very sensitive surface analytical techniques well established for many industrial and research applications.

  • 1st Year – Kinetics and Electrochemistry
  • 2nd Year – Kinetics and Electroanalytical Techniques
  • 3rd Year – Crystallography
  • Honours - Intelligent Nanomaterials and Their Applications, Design and Development of Biosensors


  • Optical, Electrochemical and Immunochromatographic Lateral Flow (Bio)Sensors Design and Developments for Point-of-Care Applications
  • Nanoelectrochemistry - methods of modifying electrode surfaces with nanomaterials and electrocatalytic materials as thin films for sensor applications. 
  • Disease biomarker detection using electrochemical and optical biosensors – design and development of cheap, sensitive and reliable electrochemical and optical diagnostic systems for the detection of biomarkers for communicable and non-communicable diseases. 
  • Nanobioconjugate strategies – methods of integrating biological molecules with nano-sized materials for the design of highly sensitive and selective novel sensors and/or biosensors.
  • Design of Lateral-Flow and Electrochemical detection systems for diagnostic applications. 


2017 Publications:

  1. Mlambo, M., Harris, R.A., Mashazi, P., Sabela, M., Kanchi, S., Madikizela, L.M., Shumbula, P.N., Moloto, N., Hlatshwayo, T.T. & Mdluli, P.S. 2017. Computational and experimental evaluation of selective substitution of thiolated coumarin derivatives on gold nanoparticles: Surface enhancing Raman scattering and electrochemical studies. Applied Surface Science, 396: 695–704. Available: http://dx.doi.org/10.1016/j.apsusc.2016.11.011
  2. Mwanza, D., Khene, S. & Mashazi, P. 2017. Tetra (4-propargyloxyphenoxy)phthalocyanines: Facile synthesis, fluorescence and thermal properties. Polyhedron, 134: 263–274. Available: http://dx.doi.org/10.1016/j.poly.2017.06.029
  3. ZO Makinde; M Louzada; P Mashazi; T Nyokong and S Khene. Electrocatalytic behaviour of surface confined pentanethio cobalt (II) binuclear phthalocyanines towards the oxidation of 4-chlorophenol. Applied Surface Science (2017), 425, 702-712.DOI: 10.1016/j.apsusc.2017.06.271. https://doi.org/10.1016/j.apsusc.2017.06.271
  4. S. S Gwebu, P.N Nomngongo, P.N Mashazi, T Nyokong, N.W Maxakato. Platinum Nanoparticles Supported on Carbon Nanodots as Anode Catalysts for Direct Alcohol Fuel Cells. International Journal of Electrochemical Science, 12 (2017) 6365 – 6378. DOI: 10.20964/2017.07.09 http://www.electrochemsci.org/list17.htm
  5. Mwanza, Daniel; Mvango, Sindisiwe; Khene, Samson; Nyokong, Tebello; Mashazi, Philani. Exploiting Click Chemistry for the Covalent Immobilization of Tetra (4-Propargyloxyphenoxy) Metallophthalocyanines onto Phenylazide-Grafted Gold Surfaces. Electrochimica Acta (2017), 254, 89-100. DOI:10.1016/j.electacta.2017.09.115. https://doi.org/10.1016/j.electacta.2017.09.115


  1. P. Mashazi, S. Vilakazi, and T. Nyokong; Design and evaluation of an electrochemical immunosensor for serodiagnosis using measles-specific Immunoglobulin G antibodies. Talanta 2013 (115) 694 – 701. http://dx.doi.org/10.1016/j.talanta.2013.06.036
  2. M. Mlambo, S. Mpelane, P.S. Mdluli, P. Mashazi, L. Sikhwivhilu, N. Moloto, and M. Moloto; Unique flexible silver dendrites thin films fabricated on cellulose dialysis cassettes.; Journal of Materials Science; 2013 (48) 6418 – 6425. http://dx.doi.org/10.1007/s10853-013-7442-2
  3. P. Mashazi, P. Tetyana, S. Vilakazi, and T. Nyokong; Electrochemical impedimetric immunosensor for the detection of measles-specific IgG antibodies after measles infections. Biosensors and Bioelectronics; 2013 (49) 32 – 38. http://dx.doi.org/10.1016/j.bios.2013.04.028
  4. P. Mashazi, N. Nombona, M. Muchindu, and S. Vilakazi; Metallophthalocyanines and metalloporphyrins as electrocatalysts: A case of hydrogen peroxide and glucose detection. Journal of Porphyrins and Phthalocyanines 2012 (16) 741 – 753. http://dx.doi.org/10.1142/s1088424612300066
  5. N. M. Sosibo, P. S. Mdluli, P. N. Mashazi, R. T. Tshikhudo, A. Skepu, S. Vilakazi S. and T. Nyokong; Facile Deposition of Gold Nanoparticle Thin Films on Semi-Permeable Cellulose Substrate. Material Letters 2012 (88) 132 – 135. http://dx.doi.org/10.1016/j.matlet.2012.08.043
  6. P. Mashazi, T. Mugadza, N. Sosibo, P. Mdluli, S. Vilakazi and T. Nyokong; The effects of carbon nanotubes on the electrocatalysis of hydrogen peroxide by metallo-phthalocyanines; Talanta 2011 (85) 2202 – 2211. http://dx.doi.org/10.1016/j.talanta.2011.07.069
  7. P. S. Mdluli, N. Sosibo, P. N. Mashazi, T. Nyokong, R. T. Tshikhudo, A. Skepu and E. van der Lingen; Selective Adsorption of PVP on the Surface of Silver Nanoparticles: A Molecular Dynamics Study. Journal of Molecular Structure 2011 (1004) 131 – 137. http://dx.doi.org/10.1016/j.molstruc.2011.07.049
  8. N. M. Sosibo, P. S. Mdluli, P. N. Mashazi, B. Dyan, T. Nyokong, R. T. Tshikhudo, A. Skepu and E. van der Lingen; Synthesis, Density Functional Theory, Molecular Dynamics and Electrochemical Studies of 3-Thiopheneacetic Acid-Capped Gold Nanoparticles. Journal of Molecular Structure 2011 (1006) 494 – 501. http://dx.doi.org/10.1016/j.molstruc.2011.09.057
  9. P. Mashazi, C. Togo, J. Limson and T. Nyokong; .Applications of polymerized metal tetra-amino phthalocyanines towards hydrogen peroxide detection. Journal of Porphyrins and Phthalocyanines 2010 (14) 252 – 263. http://dx.doi.org/10.1142/s1088424610001994
  10. P. Mashazi, E. Antunes, and T. Nyokong; Probing electrochemical and electrocatalytic properties of cobalt (II) and manganese (III) octakis(hexylthio) phthalocyanine as self-assembled monolayers. Journal of Porphyrins and Phthalocyanines 2010 (14) 932 – 947. http://dx.doi.org/10.1142/s108842461000277x
  11. P. Mashazi and T. Nyokong; Electrocatalytic studies of the covalently immobilized metal tetra-amino phthalocyanines onto derivatized screen-printed gold electrodes. Microchimica Acta 2010 (171) 321 – 332. http://dx.doi.org/10.1007/s00604-010-0438-6
  12. P. Mashazi, P. Westbroek, K. Ozoemena and T. Nyokong; Surface electrochemistry and electrochemical behaviour of tetra carboxy substituted iron, cobalt and manganese phthalocyanine monolayers on gold electrode. Electrochimica Acta 2007 (53) 1858 – 1869. http://dx.doi.org/10.1016/j.electacta.2007.08.044
  13. R. Fogel, P. Mashazi, T. Nyokong and J. Limson; Critical assessment of the quartz-crystal microbalance as an analytical tool for biosensor development and fundamental studies: metallo phthalocyanine-glucose oxidase biocomposite sensors. Biosensors and Bioelectronics 2007 (23) 95 – 101.  http://dx.doi.org/10.1016/j.bios.2007.03.012
  14. P. Mashazi, K. Ozoemena, D. Maree and T. Nyokong; Self-assembled monolayers (SAMs) of cobalt tetra-carboxylic acid chloride phthalocyanine covalently attached onto a preformed 2-mercaptoethanol SAM: A Novel Method. Electrochimica Acta 2006 (51) 3489 – 3494. http://dx.doi.org/10.1016/j.electacta.2005.10.004
  15. P. Mashazi, K. Ozoemena and T. Nyokong;Tetra-carboxylic acid cobalt phthalocyanine SAM on gold: Potential applications as amperometric sensor for H2O2 and fabrication of glucose biosensor. Electrochimica Acta 2006 (52) 177 – 186. http://dx.doi.org/10.1016/j.electacta.2006.04.056


Tel: +27 46 6038846
Fax: +2746 6225109
Email: p.mashazi@ru.ac.za
Postal Address: Department of Chemistry, Rhodes University, PO Box 94, Grahamstown, 6140, SOUTH AFRICA.
Courier Address: Room F44, Department of Chemistry, Corner of University and Artillery Roads, Rhodes University, Grahamstown, 6140, SOUTH AFRICA.

Last Modified: Tue, 06 Mar 2018 11:36:30 SAST