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Molecular chaperones in biology, medicine and protein biotechnology

The broad objective of this research is to study the mechanism by which molecular chaperones and their associated co-chaperones interact and function in cytoprotection, and to apply this knowledge in medicine and protein biotechnology. A number of research programmes are currently in progress addressing: (i) the molecular basis of chaperone-co-chaperone interactions; (ii) the role of heat shock proteins in disease (stem cells and cancer) and parasitology (malaria and trypanosomes); and (iii) improved recombinant protein over-production by co-production of chaperones.

Last Modified :Thu, 02 May 2013 12:40:28 SAST