Selected Publications

Kumar A, Casey A, Odingo J, Kesicki EA, Abrahams GL, et al. A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis. PLoS One. 2013;8(11):e72786. PubMed PMID: 24244263; PubMed Central PMCID: PMC3820577.

Abrahams GL, Kumar A, Savvi S, Hung AW, Wen S, et al. Pathway-selective sensitization of Mycobacterium tuberculosis for target-based whole-cell screening. Chem Biol. 2012 Jul 27;19(7):844-54. PubMed PMID: 22840772; NIHMSID: NIHMS393896; PubMed Central PMCID: PMC3421836.

Ahidjo BA, Kuhnert D, McKenzie JL, Machowski EE, Gordhan BG, et al. VapC toxins from Mycobacterium tuberculosis are ribonucleases that differentially inhibit growth and are neutralized by cognate VapB antitoxins. PLoS One. 2011;6(6):e21738. PubMed PMID: 21738782; PubMed Central PMCID: PMC3126847.

Warner DF, Ndwandwe DE, Abrahams GL, Kana BD, Machowski EE, et al. Essential roles for imuA'- and imuB-encoded accessory factors in DnaE2-dependent mutagenesis in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13093-8. PubMed PMID: 20615954; PubMed Central PMCID: PMC2919956.

Kana BD, Abrahams GL, Sung N, Warner DF, Gordhan BG, et al. Role of the DinB homologs Rv1537 and Rv3056 in Mycobacterium tuberculosis. J Bacteriol. 2010 Apr;192(8):2220-7. PubMed PMID: 20139184; PubMed Central PMCID: PMC2849458.

Abrahams GL, Müller P, Hensel M. Functional dissection of SseF, a type III effector protein involved in positioning the salmonella-containing vacuole. Traffic. 2006 Aug;7(8):950-65. PubMed PMID: 16800847.

Kuhle V, Abrahams GL, Hensel M. Intracellular Salmonella enterica redirect exocytic transport processes in a Salmonella pathogenicity island 2-dependent manner. Traffic. 2006 Jun;7(6):716-30. PubMed PMID: 16637890.

Abrahams GL, Hensel M. Manipulating cellular transport and immune responses: dynamic interactions between intracellular Salmonella enterica and its host cells. Cell Microbiol. 2006 May;8(5):728-37. PubMed PMID: 16611223.

Abrahams GL, Iles KD, Abratt VR. The Bacteroides fragilis NAD-specific Glutamate Dehydrogenase Enzyme is Cell Surface-Associated and Regulated by Peptides at the Protein Level, Anaerobe7:3 , 2001

Abrahams GL, Abratt VR. The NADH-dependent glutamate dehydrogenase enzyme of Bacteroides fragilis Bf1 is induced by peptides in the growth medium. Microbiology. 1998 Jun;144 ( Pt 6):1659-67. PubMed PMID: 9639936.

Last Modified: Mon, 12 Nov 2018 16:14:21 SAST