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Rhodes > BioBRU > Members > Prof. Edkins Research Group > Stacey Mattison

Stacey Mattison 

PhD Student

 

 

Research Project

Characterisation of a novel isoform of the human Hsp70/Hsp90 Organising Protein (HOP)

Comparison of the HOP gene across species and a bioinformatic analysis of the putative HOP promoter. Analysis of the transcriptional regulation of HOP by RAS and p53. The demonstration of the existence and expression of HOP-1a as a distinct and novel isoform of known HOP. A mechanistic analysis of the role of HOP-1a in cancer.

 

Publications

  1. Mattison, S.A., Blatch, G.L. & Edkins, A.L. (2017). HOP expression is regulated by p53 and RAS and characteristic of a cancer gene signature, Cell Stress and Chaperones, 22: 213-233. doi:10.1007/s12192-016-0755-8

Life outside the lab...

Stacey enjoys getting outside and exploring local landscapes with her husband and friends.

 

Contact

08w2349@campus.ru.ac.za

saweeks411@googlemail.com

 

 

Last Modified: Thu, 15 Jun 2017 09:07:27 SAST