Characterisation of a novel isoform of the human Hsp70/Hsp90 Organising Protein (HOP)
Comparison of the HOP gene across species and a bioinformatic analysis of the putative HOP promoter. Analysis of the transcriptional regulation of HOP by RAS and p53. The demonstration of the existence and expression of HOP-1a as a distinct and novel isoform of known HOP. A mechanistic analysis of the role of HOP-1a in cancer.
- Mattison, S.A., Blatch, G.L. & Edkins, A.L. (2017). HOP expression is regulated by p53 and RAS and characteristic of a cancer gene signature, Cell Stress and Chaperones, 22: 213-233. doi:10.1007/s12192-016-0755-8
Life outside the lab...
Stacey enjoys getting outside and exploring local landscapes with her husband and friends.
Last Modified: Thu, 15 Jun 2017 09:07:27 SAST