Rhodes>Pharmacy>People>Academic Staff>Prof S M M Khamanga

Prof S M M Khamanga

Dean and Head of the Faculty of Pharmacy
s.khamanga@ru.ac.za
046 6038381

Qualifications:
BSc (Swaziland),BPharm (Rhodes),MSc (Pharm)(Rhodes), PhD (Rhodes)

Professional Affiliations:

  • Swaziland Medical and Dental Council
  • Pharmaceutical Society of South Africa
  • American Association of Pharmaceutical Scientists

 

Awards and Grants:

Research Development Grants for Y-Rated Researchers


Teaching:

  • Pre-formulation Studies
  • Capsules and Microencapsulation
  • Granulation / Tableting
    Radiopharmaceuticals
  • Aerosol Dosage Forms
  • Rectal Drug Delivery Systems
    Sterilization and Disinfectants
  • States of Matter and Phase Equilibria
  • Surgical Dressings
    Blood Products
  • Disperse Systems
  • Solubility/Distribution Phenomena
  • Ionic Equilibria and Buffers

Research Interests:

  • Design of experiments and response surface methodology
  • Mathematical and statistical modelling of drug release kinetics
  • Formulation development and process optimization
  • Microencapsulation of bitter tasting drugs
  • Partial differential equations
  • Linear algebra, properties of non-negative matrices, eigenvalue problems
  • Solid state characterization of pharmaceuticals
  • Canonical analysis

Recent Publications:

  1. Vumazonke, S., Khamanga, S.M. and Ngqwala, N. (2020) Detection of Pharmaceutical Residues in Surface Waters of the Eastern Cape Province. International Journal of Environmental Research and Public Health. 2019. 17 (4067). p.1-13.
  2. Chikukwa, M.T.R. Walker, R.B. Khamanga, S.M.B (2020) Formulation and Characterisation of a Combination Captopril and Hydrochlorothiazide Microparticulate Dosage Form. Pharmaceutics. 12 (712). p.1-19.
  3. Pedzisai A. Makoni, Janeeta Ranchhod, Kasongo Wa Kasongo, Sandile M. Khamanga. Roderick B. Walker. The use of quantitative analysis and Hansen solubility parameter predictions for the selection of excipients for lipid nanocarriers to be loaded with water soluble and insoluble compounds. Saudi Pharmaceutical Journal. doi.org/10.1016/j.jsps.2020.01.010 
  4. Mazonde, P. Khamanga, S.M. and Walker, R.B. (2020) Design, Optimization, Manufacture and Characterization of Efavirenz-Loaded Flaxseed Oil Nanoemulsions. Pharmaceutics. 12 (797). p.1-22.
  5. Melamane, S, Walker, R.B. and Khamanga, S.M. (2020) Formulation optimization of smart thermosetting lamotrigine loaded hydrogels using response surface methodology, Box-Behnken design and artificial neural networks. Drug Development and Industrial Pharmacy. 46 (9). p.1402-1415.
  6. Makoni, P.A. Khamanga, S.M. and Walker, R.B. (2021) Muco-adhesive clarithromycin-loaded nanostructured lipid carriers for ocular delivery: Formulation, characterization, cytotoxicity and stability. Journal of Drug Delivery Science and Technology.61 (2021). p.1-15.
  7. Pascal Ntemi, Roderick B Walker, Sandile M Khamanga. Formulation, development and assessment of novel phyto-elastosomes loaded with Devil’s claw extract. June 2021 DOI:10.21203/rs.3.rs-631706/v1.
  8. Bwalya A. Witika *, Pedzisai A. Makoni *, Scott Kaba Matafwali, Madan S. Poka, Patrick Demana, Sandile M. Maswazi Khamanga, Siyabonga Malemane. Lipid-Based Nanocarriers for Neurological Disorders: A Review of the State-of-the-Art and Therapeutic Success to Date. Pharmaceutics 2022, 14, x. https://doi.org/10.3390/xxxxx.
  9. Bappaditya Chatterjee, Abhishek Reddy, Moushami Santra, Sandile Khamanga. Amorphization of drugs for transdermal delivery-a recent update. Pharmaceutics. 2022 May; 14(5): 983. https://doi: 10.3390/pharmaceutics14050983.
  10. Dasram, M.H.; Walker, R.B.; Khamanga, S.M. Recent Advances in Endocannabinoid System Targeting for Improved Specificity: Strategic Approaches to Targeted Drug Delivery. Int. J. Mol. Sci. 2022, 23, 13223. https://doi.org/10.3390/ijms232113223.
  11. Simise Sikhondze, Pedzisai Makoni, Roderick Bryan Walker, Sandile Khamanga. Chitosan coated metronidazole SLN for potential ocular delivery: In vitro characterization. Pharmaceutics 2023, 15(7), 1855; https://doi.org/10.3390/pharmaceutics15071855.

 

Researchgate:

https://www.researchgate.net/profile/Sandile-Khamanga


Hobbies and Interests:

  • Travelling
  • Cycling
  • Reading books
  • Cooking
  • Gardening