Dr L Goosen

Dr L Goosen

Senior Lecturer

HDE (UPE), MSc (WI) PhD (UV)

Pharmaceutical Chemistry – Senior lecturer

Room no: T4 Telephone: 0466037425 Email: mailto:l.goosen@ru.ac.za


  • Organic Medicinal and Pharmaceutical Chemistry
  • Structural Elucidation
  • Steroids
  • Photochemistry and Photostability

Current Research Projects

  • Conformational Analysis of Flavonoids
  • Chemistry and bioactivity of African Medicinal Plants
  • Chemical Education

Selected Publications

  • Y. Gaoni, A. Tomasi? and E. D. Potgieter, Stereochemistry of Addition of  Organocopper Reagents and the Hydride Ion to 1-(arylsulfonyl)bicyclo[1.1.0]butanes. J. Org. Chem., 502943 – 2947, 1985.
  • R. Chayen, Y. Mazur, H. Wyler, E. Berman, E. Potgieter and S. Goldberg, Urodiolenone from grapefruit juice, a urinary metabolite found in hypertensive subjectsPhytochemistry27(2), 369 – 372, 1988.
  • L. Spies, T.C. Koekemoer, A.A. Sowemimo, E.D. Goosen, M. Van de Venter Caspase-dependent apoptosis is induced by Artemisia afra Jacq. ex Willd in a mitochondria-dependent manner after G2/M arrestSouth African Journal of Botany 01/; 84:104, 2013
  • Luanne Venables,* Trevor. C. Koekemoer, Maryna van de Venter, and Eleonora.D Goosen. Isoalantolactone, a sesquiterpene lactone from Artemisia afra Jacq. ex Willd and its in vitro mechanism of induced cell death in HeLa cells. South African Journal of Botany 2016

Recent former students

MSc Students:

2014: Mr M Nyambe, “An Investigation of the Potential Anti-diabetic (insulinomimetic) Activity of Anti-oxidant Compounds Derived from Sargassum heterophyllumCo-supervision with Dr D.R Beukes, Rhodes University. With Distinction.


Mr Tanyi Kima : Determination of cause and mechanism of convulsive adverse effect associated with Acmella caulirhiza
Mr Hugan West:

PhD students:


2014: Mrs L Venables: “Flow cytometric applications in the investigation of the mechanism of apoptosis by extracts of and iso-alantolactone isolated from Artemisia afra Jacq. ex Willd. “ Co-supervision with Prof Maryna Van de Venter. (NMMU)
2016: Mr Théoneste Umumararungu, Synthesis and exploration of resorcinol derivatives as Plasmodium falciparum Hsp90 inhibitors. Joint supervision with Dr S D Khanye.


2013 – present: Ms Odunayo Atewolara-Odule, Department of Chemistry, faculty of Science, University of Ibadan, Nigeria, Co-supervision with supervisor: Dr. Olapeju Aiyelaagbe.

Web presence


Awards and grants

Rhodes University Vice Chancellor’s Senior Distinguished Teaching Award 2014
Academy of Pharmaceutical Sciences of South Africa Distinguished Teacher Award 2016
HELTASA / CHE National Excellence in Teaching and Learning Award 2016: Commendation
HERS-SA Academy 2016

Professional affiliations

South African Chemical Institute (SACI)
Pharmaceutical Society of South Africa (PSSA)
Southern African Biochemistry and Informatics for Natural Products (SABINA) 

Last Modified: Thu, 28 Jan 2021 01:21:48 SAST