Qualifications:
BPharm(Rhodes), MSc(Rhodes), PhD(Rhodes)

Professional affiliations:

Registered with South African Pharmacy Council

Teaching:

Pharmacology and Pharmaceutics electives

Research Interests:

Formulation, development, and delivery of poorly soluble drugs using lipid nanocarriers (SLN, NLC).

Selected Publications:

1. Witika, B.A.; Makoni, P.A.; Matafwali, S.K.; Mweetwa, L.L.; Shandele, G.C.; Walker, R.B. Enhancement of biological and pharmacological properties of an encapsulated polyphenol: Curcumin. Molecules. 2021, In Press
2. Witika, B.A.; Mweetwa, L.L.; Tshiamo, K.O.; Elder, K.; Matafwali, S.K.; Ntemi, P.V.; Chikukwa, M.T.R.; Makoni, P.A. Vesicular Drug Delivery for the Treatment of Topical Disorders: Current and Future Perspectives. J. Pharm. Pharmacol. 2021, 10.1093/jpp/rgab082, In Press
3. Witika, B.A.; Aucamp, M.; Mweetwa, L.L.; Makoni, P.A. Application of Fundamental Techniques for Physicochemical Characterizations to Understand Post-Formulation Performance of Pharmaceutical Nanocrystalline Materials. Crystals. 2021, 11, 310
4. Witika, B.A.; Makoni, P.A.; Mweetwa, L.L.; Ntemi, P.V.; Chikukwa, M.T.R.; Matafwali, S.K.; Mwila, C.; Mudenda, S.; Katandula, J.;Walker, R.B. Nano-Biomimetic Drug Delivery Vehicles: Potential Approaches for Covid-19 Treatment. Molecules. 2020
5. Makoni, P.A.; Khamanga, S.M.; Walker, R.B. Muco-adhesive Clarithromycin-Loaded Nanostructured Lipid Carriers for Ocular Delivery: Formulation, Characterization, Cytotoxicity and Stability. J Drug DelivSci Technol. https://doi.org/10.1016/j.jddst.2020.102171
6. Witika, B.A.; Makoni, P.A.; Matafwali, S.K.; Chabalenge, B.; Mwila, C.; Kalungia, A.C.; Nkanga, C.I.; Bapolisi, A.M.; Walker, R.B. Biocompatibility of Biomaterials for Nanoencapsulation: Current Approaches. Nanomaterials. 2020, 10, 1649
7. Makoni, P.A.; Wa Kasongo, K.; Walker, R.B. Preformulation studies of efavirenz with lipid excipients using thermal and spectroscopic techniques. Pharmazie 2020, 75, 417-423
8. Makoni, P.A.; Ranchhod, J.; WaKasongo, K.; Khamanga, S.M.; Walker, R.B. The use of quantitative analysis and Hansen solubility parameter predictions for the selection of excipients for lipid nanocarriers to be loaded with water soluble and insoluble compounds. Saudi Pharm. J. 2020, 28, 305–315
9. Makoni, P.A.; Chikukwa, M.T.R.; Khamanga, S.M.; Walker, R.B. Stability Indicating HPLC-ECD Method for the Analysis of Clarithromycin in Pharmaceutical Dosage Forms: Method Scaling versus Re-Validation. Sci. Pharm. 2019, 87, 31
10. Makoni, P.A.; Kasongo, K.W.; Walker, R.B. Short Term Stability Testing of Efavirenz-Loaded Solid Lipid Nanoparticle (SLN) and Nanostructured Lipid Carrier (NLC) Dispersions. Pharm. 2019, 11, 397
11. Makoni, P.A.; Khamanga, S.M.; Wa Kasongo, K.; Walker, R.B. The use of experimental design for the development and validation of an HPLC-ECD method for the quantitation of efavirenz. Pharmazie 2018, 73, 570–578

Web presence: 

LinkedIN : www.linkedin.com/in/pedzisai-makoni-33a806a9

Hobbies and interests:

Working out and watching sport