Rhodes University Animal Research Ethics Committee is registered with the National Health Research Ethics Council (NHREC) and for your research to be reviewed it must involve animal participants (animal is defined as: live, sentient non-human vertebrate, including eggs, foetuses and embryos, that is; fish, amphibians, reptiles, birds and mammals, and encompassing domestic animals, purpose-bred animals, farm animals, wildlife (see 3.28) and higher invertebrates such as the advanced members from the Cephalopoda and Decapoda; SANS 10386: 2008. p6). An application is also required if your study involves invertebrate subjects. Ethics approval is still required if carcasses are used.
You do not need to complete this application if your study involves:
Important information on animal use:
1. Moral philosophy: The ethical review of proposed animal experiments is predicated upon the acceptance by the University that, nonhuman animals are organisms fully worthy of moral concern and as such, their interests must be protected as far as possible in their use for advancement of biological knowledge and for the promotion of the health and welfare of animals and humans and protection of the environment.
2. Animal interests: In the use of animals for research, teaching and testing, animal interests obligate scientists and educators to:
3. Humaneness: The principles of humane experimental technique proposed by Russell & Burch must be followed in the planning and conduct of animal experiments.
Replacement of animals with nonsentient research models or systems, i.e. researchers should strive to avoid the use of animals if alternative methods can yield the data they need.
Reduction of the numbers of animals in experiments by design strategies that facilitate the use of the smallest number that will allow valid information to be obtained from the study and that will not be implemented at the expense of greater suffering of individual animals.
Refinement of animal sourcing, animal care practices and experimental procedures are to be adopted to minimise or remove physical and psychological distress and when this is not avoidable to counter those effects by the use of ataractics (tranquillisers), neuroleptics (dissociative agents), anaesthetics, analgesics and other effective strategies.
Responsibility, everyone using animals, whether for experimentation, testing diagnosis, teaching or sourcing of tissues or body fluids is responsible in their personal capacity for assuring that the animals
which they use are afforded the highest levels of welfare and protection from abuse, and violations of the interests accorded to them.
4. Animal protection:
Animals should be protected from research designs which involve pain, illness, isolation, mutilation (whether by surgery or otherwise) and/or premature death until such research can be demonstrated to be absolutely imperative and related to health, welfare and environmental problems which are potentially catastrophic in nature and for which alternative designs using non-sentient systems are not feasible.
Animal-based teaching and research must address an important question relevant to the University's objectives in advancing knowledge, education, science and human and animal welfare through research, be based on plausible hypothesis and have a reasonable prospect of yielding good results.
RUAREC Terms of Reference
Terms of Reference of the RUAREC
Last Modified: Thu, 29 Jul 2021 08:50:25 SAST