Leader of the BioSENs Biotechnology Research Group (Sensors, Energy and Nanomaterials Research Group)
Our research group is currently engaged in three core research areas:
• Biosensors • Biofuel Cells • Nanobiotechnology
This research is aimed at realizing innovative and commercialisable solutions in development of sensors and in accessing alternative energy from waste products. Taking an applied electrochemistry approach, much of the research seeks to harness the potential of nanostructured materials in realizing these goals.
Dr Earl Prinsloo's research focuses on the basic and applied sides of stem cell biology. Interests include the role of mitochondria in stem cell biology and the directed differentiation of stem cells into defined cell types. Stem cells hold great promise for the future of regenerative medicine. Understanding the regulatory balance that maintains stem cell self-renewal and differentiation will allow for the biotechnological exploitation of pluripotent stem cells. Dr Prinsloo believes in a systems biology approach to answering research questions using in silico, in vitro and ex vivo methods.
Dr Aileen Boshoff’s research focuses on studying fundamental aspects of molecular chaperones of parasitic origin with the aim of understanding the differences between parasitic and human systems. Through the use of modern biotechnological techniques, the role of parasitic molecular chaperones in the establishment and survival of the malarial and trypanosomal parasites
within the human host will be elucidated. The knowledge gained will be used to enhance our comprehension of this important class of proteins and improve our understanding of
the biology of these two parasites. This may contribute to the development of novel drug targets for the treatment of malaria and African Trypanosomiasis. Another broad objective is the application of molecular chaperones in protein biotechnology. The overexpression of molecular chaperones can enhance expression and solubility of recombinant proteins.
Last Modified: Thu, 08 Oct 2020 16:59:06 SAST